North Melbourne will take on Essendon, Carlton, St Kilda, Melbourne and Hawthorn during a round-robin of the new AFLX format in February.
Described as the "high-octane version of the sport", the modified game will be played across three cities in three nights, with the Roos to play at Etihad Stadium on Friday, February 16.
North trialled AFLX during its 2017 pre-season campaign, with the game consisting of two ten-minute halves, with a two-minute break at half-time.
AFLX will be played on a rectangular field with dimensions similar to that of a soccer field, with 10 players per team.
It is a seven-a-side format with three players on the bench and there is no limit to rotations.
In order to create a fast and free-flowing game, the last touch out-of-bounds rule has been introduced, while the ball will be kicked in after all scores.
To promote high scoring, the League has also introduced a 10-point super goal for majors kicked from outside the 40m arcs.
Two field umpires will adjudicate the shorter format, while two boundary umpires and two goal umpires will also be required.
Teams in the same pool will play against each other once, with the top team from each pool facing off in a Grand Final.
