North Melbourne will be forced into making at least two changes this weekend, with Jack Ziebell and Charlie Comben both unavailable due to injury.

Ziebell picked up a calf injury in last week’s clash with Sydney and was managed through the game, but hasn't come up to take on the Crows on Sunday.

After impressing with a goal on debut last week, Comben is out of the side due to a collarbone injury picked up at training on Thursday.

An extended interchange has been named, with Jared Polec, Atu Bosenavulagi, Tom Campbell, Phoenix Spicer, Shaun Atley and Lachie Young (medi-sub last week) all named as inclusions.

The Roos will fly in, fly out to Adelaide on Sunday. 

In: Jared Polec, Atu Bosenavulagi, Tom Campbell, Phoenix Spicer, Shaun Atley, Lachie Young (medi-sub last week)
Out: Jack Ziebell, Charlie Comben