The Blues sent their future second-round pick as well as pick No.43 in this year's NAB AFL Draft to GWS, in exchange for the 190cm on-baller and pick No.71.
Carlton made GWS match a bid for Setterfield at pick No.5 in the 2016 NAB AFL Draft, but has finally secured its man two years later.
Setterfield, 20, played just two matches for the Giants in his first two seasons at the club due to a number of injury setbacks.
