North Melbourne will take on Geelong on Saturday afternoon at Blundstone Arena, with the first bounce at 1.15pm AEST.
Attendees will be required to wear masks at the game.
A maximum of 10,000 seated fans will be allowed to attend.
The game will be broadcast on Fox Footy.
The AFL, together with North Melbourne and the Geelong Cats, have agreed to strict travel arrangements and other protocols as approved by the Tasmanian Government. Both clubs will fly-in and fly-out for the match on Saturday via charter flight.
Ticketing information will be provided once it becomes available.